Regulation of DNA accessibility across the cell cycle by SWI/SNF complexes [ATAC-seq]. Regulation of DNA accessibility across the cell cycle by SWI/SNF complexes [ATAC-seq]
收藏NIAID Data Ecosystem2026-03-13 收录
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To identify dynamic changes in DNA accessibility with cell-cycle phase resolution following SWI/SNF inactivation, we compared the ATAC-seq signals in IMR32 cells treated with the small-molecule catalytic inhibitor of SWI/SNF BRM014 or DMSO, which were sorted by their cell cycle stage using a FUCCI live-cell fluorescent indicator. Analysis of these locations revealed that SWI/SNF-dependent sites are regulated in cyclic patterns throughout the cell cycle. Overall design: ATAC-seq in IMR32 cells
创建时间：
2022-06-06
