Mutant FOXO1 Controls an Oncogenic Network via Enhancer Accessibility
收藏NIAID Data Ecosystem2026-05-01 收录
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Raw data used to create figures in Layden et al., Cell Genomics. 2024
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2024-03-05
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Comprehensive genomic signature of pyroptosis-related genes and relevant characterization in hepatocellular carcinoma
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DNMT3A Reads and Connects Histone H3K36me2 to DNA methylation [RNA-seq]
DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon
NIAID Data Ecosystem00
Mitochondrial Fission 1 (FIS1) knockdown effect on the H3K27Ac status of leukemia cell line MOLM-13 cells. Mitochondrial Fission 1 (FIS1) knockdown effect on the H3K27Ac status of leukemia cell line MOLM-13 cells
To examine if loss of FIS1 would alter the H3K27Ac status of leukemic cells, we used shRNA to knock down the expression of FIS1 in leukemic cell line MOLM-13 cells and performed H3K27Ac CHIP-seq to ch
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DNA dioxygenases Tet2/3 control epithelial differentiation [RNA-seq]
Execution of lineage-specific differentiation programs requires tight coordination between many regulators including Ten-eleven translocation (TET) family enzymes catalyzing 5-methylcytosine oxidation
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Stage-specific Kdm6b-transcription factor partnerships orchestrate temporal precision during stepwise motor neuron differentiation [RNA-seq]
Histone modifiers instruct cellular differentiation, yet how they achieve temporal precision remains enigmatic. Here we demonstrate that the H3K27 demethylase Kdm6b acts as a master epigenetic conduct
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