Idiopathic pulmonary fibrosis (IPF) is a progressive and life-threatening respiratory disease characterized by worsening lung function due to excessive scarring. The objective of this study was to inv
We filtered let-7b binding sites in the 3'UTRs of transcripts encoding proteins involved in fibrogenesis in Mø using online RNA databases. Briefly, we intersected the top 100 most reliable target gene
Real-time RT-PCR for profibrogenic genes. Data are means±SEM.Mann-Whitney test: *PPvs. WKY rats with HBSS treatment.The values were normalized to the GAPDH values and then expressed as relative quanti
Sequencing of LCM-derived microbiopsies from explanted lung from pulmonary fibrosis patient. Goal to assess the mutational burden, spectrum, and clonal dynamics within the tissue. Deep sampling throug
