Hepatitis C virus polymerase NS5B with saccharin inhibitor
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https://pdbj.org/mine/summary/3h5s
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Hepatitis C virus polymerase NS5B with saccharin inhibitor Descriptor: (5S)-5-tert-butyl-1-(4-fluoro-3-methylbenzyl)-4-hydroxy-3-[8-(methylsulfonyl)-1,1-dioxido-6,7,8,9-tetrahydroisothiazolo[4,5-h]isoquinolin-3-yl]-1,5-dihydro-2H-pyrrol-2-one, RNA-directed RNA polymerase Authors: Harris, S.F, Wong, A. Deposit date: 2009-04-22 Release date: 2009-09-08 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2 Å) Cite: Non-nucleoside inhibitors of HCV polymerase NS5B. Part 4: structure-based design, synthesis, and biological evaluation of benzo[d]isothiazole-1,1-dioxides Bioorg.Med.Chem.Lett., 19, 2009
创建时间：
2009-04-22
