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Additional file 2 of Single-cell multiomics of the human retina reveals hierarchical transcription factor collaboration in mediating cell type-specific effects of genetic variants on gene regulation

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Figshare2024-08-16 更新2026-04-08 收录
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Additional file 2: Table S1. The donor retina sample information. Table S2. The cell number per cell type per donor from snRNA-seq and snATAC-seq. Table S3. snATAC-seq OCR list. Table S4. The summary statistics of sc-eQTL with gene level FDR < 0.1 per cell type. Table S5. The effect size of sc-eQTL in significant retinal cell types. Table S6. The distance between eGene TSS and sc-eQTL in significant retinal cell types. Table S7. The gene expression level of transcription factors with motifs perturbed by cell type-specific sc-eQTLs. Table S8. The summary statistics of sc-caQTL with genome level FDR < 0.1 per cell type. Table S9. The effect size of sc-caQTL in significant retinal cell types. Table S10. The gene expression level of transcription factors with motifs perturbed by cell type-specific sc-caQTLs. Table S11. The master and dependent regions of sc-caQTLs across retinal cell types. Table S12. The regulatory activities of sequences tested with MPRAs. Table S13. The fine-mapped GWAS variants with PIP >0.1 and overlapped with sc-QTL and/or sc-ASCA. Table S14. The target genes of the prioritized GWAS variants with PIP >0.1 and overlapped with sc-QTL and/or sc-ASCA.

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2024-08-14
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