Crystal structure of the human BACE1 catalytic domain in complex with 4-(4-fluoro-benzyl)-piperazine-2-carboxylic acid (2-mercapto-ethyl)-amide
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Crystal structure of the human BACE1 catalytic domain in complex with 4-(4-fluoro-benzyl)-piperazine-2-carboxylic acid (2-mercapto-ethyl)-amide Descriptor: (2S)-4-(4-fluorobenzyl)-N-(2-sulfanylethyl)piperazine-2-carboxamide, Beta-secretase 1 Authors: Randal, M, Lam, M.B, Romanowski, M.J. Deposit date: 2008-03-07 Release date: 2009-01-20 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Fragment-based discovery of novel BACE1 inhibitors using Tethering technology To be Published
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2008-03-07
