官方服务：
资源简介：
PPARb/d and RXR binding was characterized in (human) monocyte derived macrophages.
应用场景：
创建时间：
2023-10-13
相关数据集
DataSheet_1_Low-density lipoprotein balances T cell metabolism and enhances response to anti-PD-1 blockade in a HCT116 spheroid model.zip
IntroductionThe discovery of immune checkpoints and the development of their specific inhibitors was acclaimed as a major breakthrough in cancer therapy. However, only a limited patient cohort shows s
NIAID Data Ecosystem30
Induction of extracellular adenosine salvage and metabolic quiescence regulate the transitional to follicular B cell checkpoint in humans.
Transcriptional profiling of transitional and follicular B cells showed that metabolic quiescence was acquired at the follicular B cell stage in both humans and mice, characterized by an orchestrated
NIAID Data Ecosystem10
Lactate Reprograms Glioblastoma Immunity through CBX3-regulated Histone Lactylation [RNA-seq]. Lactate Reprograms Glioblastoma Immunity through CBX3-regulated Histone Lactylation [RNA-seq]
Glioblastoma (GBM), an aggressive brain malignancy with a cellular hierarchy dominated by GBM stem cells (GSCs), evades anti-tumor immunity through mechanisms that remain incompletely understood. Like
NIAID Data Ecosystem00
Immunoediting instructs tumor metabolic reprogramming to support immune evasion [smartseq]
Immunoediting sculpts immunogenicity and thwarts host anti-tumor responses in tumor cells during tumorigenesis; however, it remains unknown whether metabolic programming of tumor cells can be guided b
NIAID Data Ecosystem20
Vitamin B6 competition in the tumor microenvironment hampers antitumor functions of NK cells
Nutritional factors play crucial roles in immune responses. The tumor-caused nutritional deficiencies are known to affect anti-tumor immunity. Here, we demonstrate that pancreatic ductal adenocarcinom
NIAID Data Ecosystem00
