Defense Response

This knowledge graph centres on OsWRKY7 (gene OS02G0462800, Oryza sativa japonica), a WRKY-family transcription factor queried against the keyword filter "defense". The network spans 262 nodes and 612 edges across multiple species — including rice (O. sativa), Arabidopsis thaliana, wheat (Triticum aestivum/durum), barley (Hordeum vulgare), maize (Zea mays), Brachypodium distachyon, and sorghum (Sorghum bicolor) — reflecting the broad evolutionary conservation of this gene family. The seed gene's protein product OS02T0462800-01 connects via sequence similarity to a cluster of functionally characterized WRKY paralogs and orthologs, including OsWRKY51, OsWRKY10, and OsWRKY42 in rice, as well as AtWRKY7, AtWRKY11, and AtWRKY17 in Arabidopsis. Evidence paths link these genes to key biological processes such as Defense Response, Regulation Of Defense Response, defence response to fungi, defence response to bacteria, and phytoalexin biosynthesis, supported by 58 publications (16 currently visible) spanning 2000–2025. Curated phenotype annotations further connect the network to jasmonic acid signalling, basal defense, nematode resistance, and salt/drought stress tolerance, illustrating the dual roles these transcription factors play in both biotic and abiotic stress responses.