Altered metabolism fuels two hallmark properties of cancer cells, unlimited proliferation and differentiation blockade. AMP-activated protein kinase (AMPK) is a master regulator of bioenergetics cruci
Overnight cultures of wild-type yeast were diluted in fresh medium with or without 10 mM sodium crotonate in the presence of 0.8 M sorbitol. After 3.5 hours cells were in early log-phase (1 Ã 10^7 ce
Monocarboxylates are important energy metabolites for oxidative cells and act as signaling molecules on various cell types. The goal of this project was to study the effects of L-lactate and pyruvate,