Stepwise histone replacement by SWR1 requires dual activation with histone H2A.Z and canonical nucleosome

ChEBI2010-10-12 更新2026-07-21 收录

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组蛋白交换机制

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Stepwise histone replacement by SWR1 requires dual activation with histone H2A.Z and canonical nucleosome

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2010-10-12

The nucleosomal barrier to promoter escape by RNA Polymerase II is overcome by the chromatin remodeler Chd1 [HiSeq]. Mus musculus

染色质重塑

核小体周转

We use a metabolic labeling strategy for directly measuring nucleosome turnover to determine the role of chromatin remodeler Chd1 on chromatin dynamics in mouse embryonic fibroblasts expressing with w

NIAID Data Ecosystem90

The TRIPLE PHD FINGERS proteins are required for SWI/SNF complex-mediated +1 nucleosome positioning and transcription start site selection in Arabidopsis [RNA-seq]. The TRIPLE PHD FINGERS proteins are required for SWI/SNF complex-mediated +1 nucleosome positioning and transcription start site selection in Arabidopsis [RNA-seq]

染色质重塑

RNA测序

In eukaryotes, DNA is associated with histones to form nucleosomes, the basic component of the chromatin. This structure presents a physical barrier for nuclear proteins to access DNA and, therefore,

NIAID Data Ecosystem70

The histone variant H2A.Z in yeast is almost exclusively incorporated into the +1 nucleosome in the direction of transcription

组蛋白变体定位

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To investigate the incorporation dynamics of histone variant H2A.Z, we determined its genomic localization at single nucleosome resolution, as well as the localization of its chromatin remodelers Swr1

NIAID Data Ecosystem40

Incomplete MyoD-induced transdifferentiation is mediated by chromatin remodeling deficiencies [RNA-Seq]. Homo sapiens

细胞转分化

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MyoD is known to transdifferentiate fibroblasts into muscle-like cells. Despite phenotypic resemblance and expression of myogenic marker genes in transdifferentiated cells, our global gene expression

NIAID Data Ecosystem80

The chromatin remodelling factor ATRX suppresses R-loops in transcribed telomeric repeats

R-loop调控

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ATRX is a chromatin remodelling factor found at a wide range of tandemly repeated sequences including telomeres (TTAGGG)n. Acquired mutations in ATRX are found in nearly all tumours which maintain the

NIAID Data Ecosystem50

Stepwise histone replacement by SWR1 requires dual activation with histone H2A.Z and canonical nucleosome

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