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Transcriptome changes in human PSC-derived cardiomyocytes induced by doxorubicin II

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP489184
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资源简介:
Doxorubicin (DOX) is one of the most effective chemotherapeutic agents for various types of cancers. However, DOX often causes cardiotoxicity referred to as DOX-induced cardiomyopathy (DIC). In this experiment, transcriptome changes induced by doxorubicin were examined in human PSC-derived cardiomyocytes. Overall design: Global gene expression changes were examined using RNA-seq in human PSC-derived cardiomyocytes with 1 µM doxorubicin or DMSO control treatement for 24h.
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2026-02-08
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