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Transcriptome analysis of mice dermal white adipose tissue during aging

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Dermal white adipose tissue (dWAT) is one of the peripheral tissues directly adjacent to hair follicle(HF) and acts as critical macroenvironmental niche of HF. dWAT directly contribute to HF aging by paracrine signals secretion. However, the altered interrelationship between dWAT and HF with aging has not been thoroughly understood Here, through microdissection, we separated dWAT from skin of aged mice (18 months) and young mice (2 months) in telogen and depilation-induced anagen for transcriptome comparing.

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