The high-intensity interval training mitigates the cardiac remodeling in spontaneously hypertensive rats

As an initial effort to test the hypothesis that HIIT is a viable non-pharmacological alternative for cardioprotection, we analyzed the effects of HIIT during the compensated phase of hypertension on the structural (anatomical data, echocardiography), functional (echocardiography, isolated papillary muscle), and MAPK signaling (gene expression) of myocardial remodeling in SHRs.

作为对高强度间歇训练（HIIT）作为一种可行的非药物性心脏保护替代方案的初步检验，本研究分析了HIIT在高血压代偿期对心肌重塑的结构（解剖数据、超声心动图）、功能（超声心动图、孤立乳头肌）以及MAPK信号通路（基因表达）的影响。