EPZ-6438/GRag combination increases EPZ-6438 sensitivity in <i>EZH2</i> Y646 mutant cell lines and overcomes insensitivity in cell lines resistant to EZH2 inhibition.
收藏NIAID Data Ecosystem2026-03-09 收录
数据链接：
官方服务：
资源简介：
Values in the table represent EPZ-6438 mean IC50 values ± SEM (at least n = 2) for the indicated time points and dosing schedules. EPZ-6438 IC50 values were not extrapolated beyond the highest and lowest doses of EPZ-6438 (1 µM, and 0.004 µM, respectively). In cases where IC50 values could not be averaged due to non-extrapolated values, all replicates are listed. GRag: glucocorticoid receptor agonist, Pred: Prednisolone. EPZ-6438/GRag combination increases EPZ-6438 sensitivity in EZH2 Y646 mutant cell lines and overcomes insensitivity in cell lines resistant to EZH2 inhibition.
创建时间：
2014-12-10
