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Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl-amide scaffold

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl-amide scaffold Descriptor: 3-amino-N-(2'-amino-6'-methyl[4,4'-bipyridin]-3-yl)-6-(2-fluorophenyl)pyridine-2-carboxamide, DI(HYDROXYETHYL)ETHER, Serine/threonine-protein kinase pim-1 Authors: Bellamacina, C, Bussiere, D, Burger, M. Deposit date: 2016-03-01 Release date: 2016-04-06 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Design, synthesis and structure activity relationship of potent pan-PIM kinase inhibitors derived from the pyridyl carboxamide scaffold. Bioorg.Med.Chem.Lett., 26, 2016
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2016-03-01
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