Supplementary Material for: Prevalence of frailty in the TIA clinic and its associations with mortality

Introduction
Frailty is a clinical syndrome of increased vulnerability to stressors. Frailty is associated with adverse outcomes after stroke, but frailty and transient ischaemic attack (TIA) are less well described.
Methods
Retrospective analysis of patients referred by the emergency department (ED) to TIA clinic (01/01/2016-12/03/2022), linked to hospital records for electronic follow-up. Only those with Clinical Frailty Scale (CFS) recorded within two weeks of clinic were included. Prevalence of frailty was determined based on CFS score >4. Hazard ratios (HR) for mortality were determined through Cox proportional hazard regression, adjusted for prognostic factors. Where repeat CFS data were available, temporal change in frailty was recorded (~15 months).
Results
Of 1185 patients included, 53.5% (n=634) had frailty. Patients with frailty tended to be older (median age 81 vs 74 years, p

引言
衰弱是一种对压力源敏感性增加的临床综合征。衰弱与卒中后的不良预后相关，但衰弱与短暂性脑缺血发作（TIA）的描述尚不充分。
方法
对2016年1月1日至2022年12月3日期间急诊科（ED）转诊至TIA门诊的患者进行回顾性分析，并与医院记录进行电子跟踪链接。仅包括在就诊两周内记录有临床衰弱量表（CFS）的患者。衰弱的患病率基于CFS评分大于4进行确定。通过Cox比例风险回归分析，确定了死亡风险的危害比（HR），并对预后因素进行调整。对于可重复的CFS数据，记录了衰弱的时间变化（约15个月）。
结果
在包括的1185名患者中，53.5%（n=634）存在衰弱。衰弱患者倾向于年龄较大（中位数年龄81岁 vs 74岁，p