PROX1 Orchestrates Tumor Metabolic Plasticity by Integrating LKB1-AMPK Signaling with BCAA Catabolism

NIAID Data Ecosystem2026-03-14 收录

肿瘤代谢可塑性

LKB1-AMPK信号通路

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE214194 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2023-01-03

PROX1 Orchestrates Tumor Metabolic Plasticity by Integrating LKB1-AMPK Signaling with BCAA Catabolism (RNA-Seq)

肿瘤代谢可塑性

PROX1基因功能

Tumor cell metabolic plasticity is essential for tumor progression and therapeutic response, but the mechanism for regulation of metabolic plasticity remain poorly explored. Here, we identify PROX1 as

NIAID Data Ecosystem40

PROX1 Orchestrates Tumor Metabolic Plasticity by Integrating LKB1-AMPK Signaling with BCAA Catabolism. PROX1 Orchestrates Tumor Metabolic Plasticity by Integrating LKB1-AMPK Signaling with BCAA Catabolism

肿瘤代谢可塑性

信号通路调控

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem20

Supplementary Table S2 from Expression of IMPACT Curtails Metabolic Plasticity and Augments NK Cell Killing to Abrogate Metastatic Growth

肿瘤代谢可塑性

抗氧化基因表达调控

Fold change in antioxidant responsive genes upon GCN1 KD in KPC cells grown at physiologic levels of glutamine

NIAID Data Ecosystem10

Proteomics Indicates Lactate Dehydrogenase is Prognostic in Acetaminophen-induced Acute Liver Failure Patients and Reveals a Role for LKB1-AMPK Signaling

肝衰竭预后生物标志物

LKB1-AMPK信号通路

Better biomarkers to predict death early in acute liver failure (ALF) are needed. To that end, we obtained early (study day 1) and later (day 3) serum samples from transplant-free survivors (n=28) and

NIAID Data Ecosystem20

PROX1 Orchestrates Tumor Metabolic Plasticity by Integrating LKB1-AMPK Signaling with BCAA Catabolism (ATAC-Seq). PROX1 Orchestrates Tumor Metabolic Plasticity by Integrating LKB1-AMPK Signaling with BCAA Catabolism (ATAC-Seq)

肿瘤代谢可塑性

ATAC-seq分析

NIAID Data Ecosystem10