Expression profiles of bone marrow cells from model mice for erythropoietin-deficiency anemia (ISAM)
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE43585
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资源简介:
We established a novel mouse model for postnatal erythropoietin (Epo)-deficiency anaemia, designated ISAM (inherited super anemic mouse), using a transgenic complementation rescue technique. To identify Epo-regulated genes in vivo, we examined the mRNA expression profile in the bone marrow of ISAM 6 hours after recombinant human EPO (rHuEPO) administration. Erythropoietin-induced gene expression in mouse bone marrow was measured at 6 hours after rHuEPO administration (3,000 U/kg). Three Epo-treated samples were analyzed, and two PBS-treated and one untreated samples were used as a control group.
创建时间:
2017-01-12



