Proportions of the ApoE4 allele carriers, mean age at the time of biospecimens collection, and the allele-specific proportions of deaths, CVD, cancer, and ND for the genotyped participants of the FHS, FHSO, and LLFS.

FHS = the Framingham Heart Study (FHS) original cohort; FHSO = the FHS offspring cohort.LLFS_P = long-living parental generation of the Long Life Family Study (LLFS) participants; LLFS_O = offspring of the LLFS long-living participants; LLFS_S = spouses of the LLFS long-living participants and their offspring.CVD = cardiovascular diseases including diseases of heart and stroke; Cancer = all sites but skin; ND = dementia and Alzheimer disease combined; SD = standard deviation.*proportion of the ApoE4 allele carriers is in percentages;**maximal sample size; the number of individuals with non-missing information on ND is about 1% less in the FHS and about 3% less in the FHSO.***age at biospecimens collection at the 19th FHS, 4th FHSO and baseline LLFS examinations.The ApoE4-allele-specific proportions of CVD, cancer, and ND are not given for the LLFS because this information was not used in this paper.