Pulsed peritoneal dialysis in Sprague-Dawley rats

Peritoneal dialysis treatment is hampered by low small solute clearances compared to hemodialysis. Previous data have indicated that stirring or mixing of the dialysate could possibly improve small solute diffusion, presumably by avoiding the formation of stagnant layers in the dialysate directly adjacent to the peritoneal membrane. In an experimental model of peritoneal dialysis in Sprague-Dawley rats, we compared a 60 min standard PD-exhange with a novel exchange technique called pulsed peritoneal dialysis in which the dialysate in pulsed  in and out of the peritoneal cavity without the addition of fresh dialysis fluid. Samples of dialysate were taken directly after instillation and after 60 min. Samples of blood were taken before and after dialysis., , , # Pulsed peritoneal dialysis in Sprague-Dawley rats

[https://doi.org/10.5061/dryad.80gb5mkx1](https://doi.org/10.5061/dryad.80gb5mkx1)

Principal Investigator
Name: Carl M. Öberg
ORCID: 0000-0002-2471-6914
Institution: Lund University
Address: Njurmottagningen SUS Lund, Barngatan 2, 22184 Lund, SWEDEN
Email: [[e-mail]](mailto:[e-mail])

Author/Associate or Co-investigator Information
Name: Helén Axelberg
ORCID: NA
Institution: Lund University
Address: NA
Email: [[e-mail]](mailto:[e-mail])

Date of data collection: 2023-08-29 to 2023-10-12

Geographic location of data collection: Lund, Sweden

## Description of the data and file structure

DATA-SPECIFIC INFORMATION FOR: ppd.csv

Methods for processing the data: Saved as a CSV file from Microsoft Excel

Number of variables: 96

Number of cases/animals: 24

Variable List:
animal, \"Unique number assigned to each rat\"
treatment, \"Treatment/intervention given to the animal\"
date, \"Date ...