IHC: Score denotes the abundance of PrPd in each visceral tissue; no labelling (−), mild (+), moderate(++) or severe accumulation (+++) of PrPd. For muscle samples a semi-quantitative scoring system w
Hypoglycemia resulted in an increase of brain water content. # pHypo: hypoglycemia, Sham Hypo: sham hypoglycemia. Hypo + R: hypoglycemia + recovery. Data are shown as mean ± SD.Measurment of brain cor
Number of mouse brains and spleens positive for PrPres on WB and/or prion seeding activity in RT-QuIC per total number of samples tested within each respective group.