<b>Acetyl Tributyl Citrate Inhalation Exposure Promotes Idiopathic Pulmonary Fibrosis via Targeting MMP1/CTSB</b>
收藏NIAID Data Ecosystem2026-05-10 收录
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We predicted targets of ATBC and its metabolites through computational toxicology, screened core targets from IPF clinical transcriptome data via machine learning and network topology analysis, simulated compound-target interactions by molecular docking, and performed an exploratory pilot experiment in bleomycin-induced fibrotic mice to observe the trend of effects of intratracheal ATBC at different doses on lung pathology and MMP1 expression.
创建时间：
2026-03-29
