Severe malaria definitions for reporting of SAEs.

1The lowest value recorded by either centrifuge or Coulter counter at any point during the admission was used to determine a case. 2The coma-score was assessed after correction of hypoglycemia and 60 minutes after control of fits. If fitting could not be controlled within 30 minutes the child was diagnosed with cerebral malaria. 3Two or more generalized convulsions within a 24-hour period prior to admission. 4Inability to sit unaided. 5<2.2 mmol/dL.