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Survival of RML-infected CD-1 mice treated with AAV2-PrP-shRNA and GSI/Qa was very similar to that of untreated control mice.

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Figshare2015-12-02 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_Survival_of_RML_infected_CD_1_mice_treated_with_AAV2_PrP_shRNA_and_GSI_Qa_was_very_similar_to_that_of_untreated_control_mice_/1038242
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4 µl of AAV2-PrP-shRNA was infused to the thalamus bilaterally at 50 dpi and the next day, AAV-infused mice were treated with 5 mg/kg/day of GSI and 40 mg/kg/day of Qa for 28 days. The average survival time was calculated based on the onset of prion disease. Mice were euthanized one day after they showed scrapie-sick symptoms.
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2015-12-02
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