RNA-seq investigation of overexpression and knockdown of SCD expression in goose granulosa cells

Recently, the role of stearoyl-CoA desaturase (SCD) as a regulator of fatty acid desaturation in goose GCs was identified, whereby metabolite changes in lipid-related metabolism, was found to be closely related to follicular development. Transcriptomics provided differentially expressed genes (DEGs), part of which were assigned to lipid-related Gene Ontology slim terms. These results provide new evidence that altered SCD expression changed GC genes, and regulated relevant metabolic pathways, which may implicate SCD as one of the major genes in the regulation of lipid secretion of goose GCs.