Effect of nsSNPs on the structure and function of protein predicted by Mutpred2.

NIAID Data Ecosystem2026-03-13 收录

数据链接：

https://figshare.com/articles/dataset/Effect_of_nsSNPs_on_the_structure_and_function_of_protein_predicted_by_Mutpred2_/17044462 数据链接链接失效反馈

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资源简介：

Effect of nsSNPs on the structure and function of protein predicted by Mutpred2.

创建时间：

2021-11-18

Structure-informed direct coupling analysis improves protein mutational landscape predictions

蛋白质突变预测

结构信息整合计算模型

Data repository for StructureDCA Data repository for the publication:Matsvei Tsishyn, Hugo Talibart, Marianne Rooman, Fabrizio Pucci. Structure-informed direct coupling analysis improves protein muta

Zenodo2026-03-16 更新70

TopVIP_input_output

蛋白质突变预测

生物信息学

All the datasets tested in the article "Accurate top protein variant discovery via low-N pick-and-validate machine learning".

Figshare2023-12-19 更新40

Table_2_Predicting the Disease Risk of Protein Mutation Sequences With Pre-training Model.XLSX

蛋白质突变预测

疾病风险评估

Accurately identifying the missense mutations is of great help to alleviate the loss of protein function and structural changes, which might greatly reduce the risk of disease for tumor suppressor gen

NIAID Data Ecosystem30

SeprotHub/Dataset-RASH_HUMAN

蛋白质突变预测

深度突变扫描

该数据集包含了人类RASH蛋白质单点突变及其对应的突变效应分数，这些分数来自于深度突变扫描实验。蛋白质的格式为氨基酸序列。数据集分为训练集、验证集和测试集，分别包含2479、338和317个样本。标签表示基于深度突变扫描实验的每个蛋白质的突变效应分数，范围从负无穷大到正无穷大，其中0代表野生型的值，数值越大表示适应性越高。

Hugging Face2025-05-13 更新70

May_Based功能约束蛋白突变稳定性研究数据集

蛋白质突变预测

功能约束蛋白分析

本数据集为May等人相关研究的汇总数据，包含基于错义变异稳定性破坏估计的全基因组功能约束指标，用于分析功能受限人类蛋白质对单氨基酸替换突变稳定性的敏感性差异，共含一份文件。 May等人研究论文"Functionally constrained human proteins are less prone to mutational instability from single amino acid

海数据40

Effect of nsSNPs on the structure and function of protein predicted by Mutpred2.

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