NSD2 promotes HCC metastasis through methylating PKM2 and activating SF3B1-dependent alternative splicing
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https://www.ncbi.nlm.nih.gov/sra/SRP616506
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To investigate the effect of SF3B1K333 lactylation on alternative splicing, we performed genome-wide differential alternative splicing events (ASEs) analysis. We conducted RNA-seq on lactate-treated Huh-7 cells overexpressing either SF3B1WT or the lactylation-deficient SF3B1K333R mutant.
创建时间：
2025-09-30
