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A developmental model of human early cardiac valvulogenesis. A developmental model of human early cardiac valvulogenesis

NIAID Data Ecosystem2026-03-09 收录

心脏瓣膜发育

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA297437 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2015-09-30

心脏瓣膜发育

Notch信号通路

Our studies identify a mechanism of signaling crosstalk during valve morphogenesis that sheds light on the origin of congenital heart defects associated with reduced Notch function. Aortic and pulmona

NIAID Data Ecosystem50

Comparisons between the valve cluster and published datasets.

心脏瓣膜发育

差异基因表达分析

Sheet 1: comparison of top 250 DEGs from Queen data (this manuscript) to DeLaughter et al (2013). Shared genes are in red. Sheet 2: list of top 250 DEGs from Queen data (this manuscript) and Asp et al

Figshare2023-11-27 更新30

Endocardial Brg1 disruption illustrates the EMT origins of semilunar valve disease

心脏瓣膜发育

内皮-间充质转化(EMT)

Discreet defects during prenatal semilunar valve (SLV) development frequently progress to pathological states later in life and often require valve replacement surgery. As such, it is challenging to d

Alliance of Genome Resources10

Gene expression analysis of human heart valves

心脏瓣膜发育

弹性纤维

Semilunar valve leaflets have a well-described trilaminar histoarchitecture with a sophisticated elastic fiber network. It was previously proposed that elastin-containing fibers play a subordinate rol

NIAID Data Ecosystem50

Expression data from embryonic day 15.5 atrioventricular canal regions were isolated from Scx-/- and Scx+/+ mice.

心脏瓣膜发育

基因表达调控

Purpose: Our lab has previously shown that Scleraxis (Scx) is require for proper valve development in vivo. In order to fully explore gene networks regulated by Scx during the vital stages of valve re

NIAID Data Ecosystem20

A developmental model of human early cardiac valvulogenesis. A developmental model of human early cardiac valvulogenesis

资源简介：

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