Metabolism-related variables in 100 patients with type-1 diabetes before and after one year of treatment with metformin or placebo.

Data at baseline (0 month) and EOT (12 months) are raw absolute values given as mean (standard deviation). Data for ΔMetformin and ΔPlacebo represent the mean (95% confidence interval) estimated changes from baseline as predicted by the statistical model. The numbers of patients represent the maximum number of patients included in each analysis. Data are presented as intention-to-treat including last observation carried forward.
Abbreviations:
EOT: End of treatment.