Effect of P7C3-A20 treatment on gene expression after intracerebral hemorrhage injury

To investigate the effect of P7C3-A20 on gene expression after intracerebral hemorrhage injury, we employed RNA sequencing (RNA-seq) to profile the mRNA expression ensuing P7C3-A20 treatment after ICH. Different gene distribution could be clearly seen on the volcano plot between diferent comparisions among Sham, ICH, and ICH+P7C3-A20 group. Finally, we showed that 1047 shared genes overlapping between those differentially expressed genes, which was reversed by P7C3-A20 treatment Overall design: Experimental mice were randomly and equally divided into three groups: sham group, ICH group, ICH + P7C3-A20 group. At 3 days after diferent treatments, 3 mice were randomly selected from each group and used to perform RNA sequencing.