Crystal structure of human Pim-1 kinase in complex with a thiadiazolamine-indole inhibitor.
收藏Protein Data Bank Japan2023-12-27 更新2026-03-21 收录
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Crystal structure of human Pim-1 kinase in complex with a thiadiazolamine-indole inhibitor. Descriptor: 6-[5-(5-amino-1,3,4-thiadiazol-2-yl)-1H-indol-3-yl]-N-cyclopentylpyridin-2-amine, GLYCEROL, Serine/threonine-protein kinase pim-1 Authors: Mohr, C. Deposit date: 2014-10-29 Release date: 2015-02-11 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Discovery of 5-(1H-indol-5-yl)-1,3,4-thiadiazol-2-amines as potent PIM inhibitors. Bioorg.Med.Chem.Lett., 25, 2015
创建时间：
2014-10-29
