Single-nuclei sequencing of late gestation rhesus macaques exposed to chorioamnionitis

We used single-nuclei sequencign to determine the effect of chorioamnionitis to the developing cerebellum using a rhesus macaque model of chorioamnionitis induced by intra-amniotic LPS. Overall design: Cerebellar hemispheres were sampled from rhesus macaque fetuses at 130-133 days of gestation 5 days after exposure to 1mg of intra-amniotic LPS or controls without intervention