The double stranded RNA binding protein Adad1 (adenosine deaminase domain containing 1) is a member of the adenosine deaminase acting on RNAs (Adar) protein family with germ cell-specific expression.
Loss of function of cyclin E1 or E2, important regulators of the mitotic cell cycle, yields viable mice, but E2-deficient males display reduced fertility. To elucidate the role of E-type cyclins durin
n the present study we identify Zebrafish Hsf5 and show that it is required for proper spermatogenesis. The hsf5 mutants are male sterile and have malformed sperms. We proved evidences that Hsf5 is re