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Dipyridamole binds to the N-terminal domain of human Hsp90A

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Protein Data Bank Japan2023-11-29 更新2026-03-21 收录
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Dipyridamole binds to the N-terminal domain of human Hsp90A Descriptor: 2-[[2-[bis(2-hydroxyethyl)amino]-4,8-di(piperidin-1-yl)pyrimido[5,4-d]pyrimidin-6-yl]-(2-hydroxyethyl)amino]ethanol, CHLORIDE ION, Heat shock protein HSP 90-alpha, ... Authors: Shi, L, Zhou, C, Zhong, Y, Gao, J, Zhou, H, Zhang, N. Deposit date: 2020-12-03 Release date: 2021-12-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (2.34 Å) Cite: Dipyridamole interacts with the N-terminal domain of HSP90 and antagonizes the function of the chaperone in multiple cancer cell lines. Biochem Pharmacol, 207, 2022
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2020-12-03
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