Gene expression profile at single cell level of tumoral immune cells sorted from MB49 tumor tissues of wt and Lcn2 ko chimeric mice. Gene expression profile at single cell level of tumoral immune cells sorted from MB49 tumor tissues of wt and Lcn2 ko chimeric mice

Lcn2 was found as a marker of senescent neutrophils and to affect the tumor growth in our research. We used single cell RNA sequencing (scRNA-seq) to analyze the immune cells diversity and function change with Lcn2 knock-out Overall design: To investigate the the importance of Lcn2 to the neutrophils diversity and function, we performed single cell RNA-sequencing analysis by using BD Rhapsody system from immune cells sorted from MB49 tumor tissues of wt and Lcn2 ko chimeric mice