five

Transcriptome changes under IL-10 stimulation in HBZ-transgenic mice

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https://www.ncbi.nlm.nih.gov/sra/DRP006149
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We found IL-10 significantly accelerated the proliferation of CD4+ T cells from HBZ-Tg mice. These results indicated that HBZ makes cells sensitive to an IL-10 signaling pathway that promotes proliferation. To investigate the molecules and pathways that are cooperatively regulated by HBZ and IL-10, we carried out transcriptional profiling by RNA-seq.
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2020-06-04
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