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Targeting tumor immune microenvironment enhances anti-tumor activity of KRAS G12D Inhibitor RNK08954

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NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP649196
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The effect of RNK08954 on modulating the tumor immune microenvironment (TIME) was studied in immune-competent mouse syngeneic model. RNK08954 administration at a dose of 100 mg/kg exhibited best response in subcutaneous CT-26-derived mouse syngeneic model. Immune phenotyping of tumor samples 24 hours post-dose using a single cell RNA-sequence (scRNA-seq).
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2026-01-01
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