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Sexually dimorphic effects of ADNP mutation and Davunotide treatment on mice hippocampal transcriptome

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE272331
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ADNP haplo-insufficient (Adnp +/- ) mice or CRSIPR/Cas9 edited to carry the most prevalent neurodevelopmental ADNP syndrome mutation, p.Tyr718*. A subgroup was treated the ADNP fragment, investigational drug, NAP (davunetide). RNA was extracted from 2.5-month-old Tyr mouse hippocampi, treated, handled, sequenced on NextSeq500 (Illumina, CA, USA).
创建时间:
2025-05-31
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