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Interplay between nutrient stress and lysosomal signaling imprints immune memory in tissues [microarray3]

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NIAID Data Ecosystem2026-05-02 收录
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Uncovered organelle signaling and metabolic processes shaping CD8+ tissue-resident memory (TRM) development OT-1 cells from WT-Cas9-KI-Flcnfl/fl or Cd4Cre-Cas9-KI-Flcnfl/fl mice were transduced with sgNTC, sgTfeb, or sgTfe3 in various combinations as indicated and transferred into WT mice, followed by LM-OVA infection. At day 7.5 p.i., siIEL OT-1 cells were sort purified for microarray analysis

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2025-01-16
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