Crystal Structure of the PDE4D Catalytic Domain and UCR2 Regulatory Helix with BPN14770
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Crystal Structure of the PDE4D Catalytic Domain and UCR2 Regulatory Helix with BPN14770 Descriptor: (4-{[2-(3-chlorophenyl)-6-(trifluoromethyl)pyridin-4-yl]methyl}phenyl)acetic acid, 1,2-ETHANEDIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... Authors: Fox III, D, Fairman, J.W, Gurney, M.E. Deposit date: 2019-01-03 Release date: 2019-05-08 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Design and Synthesis of Selective Phosphodiesterase 4D (PDE4D) Allosteric Inhibitors for the Treatment of Fragile X Syndrome and Other Brain Disorders. J.Med.Chem., 62, 2019
创建时间:
2019-01-03



