five

Crystal structure of human tankyrase 2 in complex with 1-methyl-7-phenyl-1,2,3,4,5,6-hexahydro-1,6- naphthyridin-5-one

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Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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Crystal structure of human tankyrase 2 in complex with 1-methyl-7-phenyl-1,2,3,4,5,6-hexahydro-1,6- naphthyridin-5-one Descriptor: 1-methyl-7-phenyl-2,3,4,6-tetrahydro-1,6-naphthyridin-5(1H)-one, GLYCEROL, SULFATE ION, ... Authors: Haikarainen, T, Lehtio, L. Deposit date: 2014-08-18 Release date: 2015-06-10 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Structure-based design, synthesis and evaluation in vitro of arylnaphthyridinones, arylpyridopyrimidinones and their tetrahydro derivatives as inhibitors of the tankyrases. Bioorg.Med.Chem., 23, 2015
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2014-08-18
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