Differential gene expression analysis of key metabolic pathways between Trypanosoma cruzi strains.

The functional categories analyzed are listed in the first column; with the identities of genes within these categories provided in S3 Table. The total number of mRNAs that are at least three-fold differentially expressed between three pair-wise comparisons are shown in the next three columns. For the Esmeraldo vs. Sylvio X10 comparison, the percentage of analyzed T. cruzi genes that were found to be differentially expressed for each category is also shown. If the categories contained two or more differentially expressed Esmeraldo vs. Silvio X10 genes, the directionality of the regulation is presented (up or down). For regulation to be considered directional, zero or one gene only was permitted to be regulated in the opposite direction as the rest of the differentially expressed genes within that category. Strains analyzed are CL Brener (CLB); Sylvio X10 (Syl); Esmeraldo (Esm).