Overview of Analytical-to-Preparative Liquid Chromatography Method Development
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https://figshare.com/articles/dataset/Overview_of_Analytical-to-Preparative_Liquid_Chromatography_Method_Development/9228143
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资源简介:
Purification
of compounds is a necessary aspect of chemical synthesis.
Developing an efficient purification method is time-consuming. A method
that quickly calculates preparative gradients from analytical scouting
runs is described. A solvent composition that provides the desired
retention of a model compound is used to calibrate the analytical
scouting run to determine an apparent gradient delay. This delay is
applied to the retention times of compounds run with the same scouting
gradient to yield a solvent composition for preparative purification.
创建时间:
2019-07-22



