BIOGRID CURATED DATA FOR ACT-2 (Caenorhabditis elegans)

Protein-Protein, Genetic, and Chemical Interactions for ACT-2 (Caenorhabditis elegans) curated by BioGRID (https://thebiogrid.org); DEFINITION: act-2 encodes one of five C. elegans actins; act-2 functions redundantly in early embryonic cortical microfilaments with act-1 and act-3, and dominant mutations in act-2 result in uncoordinated locomotion; an ACT-2::GFP reporter fusion is expressed in the cytoplasm of embryonic cells and is also found in contractile filaments in adult muscle cells.

由 BioGRID (https://thebiogrid.org) 精心编辑的 ACT-2（秀丽隐杆线虫 Caenorhabditis elegans）蛋白质-蛋白质、遗传及化学相互作用数据集；定义：act-2 编码五种秀丽隐杆线虫肌动蛋白之一；act-2 在早期胚胎皮质微丝中与 act-1 和 act-3 发生功能冗余，其显性突变导致运动不协调；ACT-2::GFP 报告基因融合蛋白在胚胎细胞质中表达，并在成年肌细胞收缩丝中亦有所发现。