G0S2 functions as a tumor supressor through represssion of Myc signaling pathways

ChEBI2016-06-01 更新2026-07-12 收录

肿瘤抑制基因

Myc信号通路调控

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G0S2 functions as a tumor supressor through represssion of Myc signaling pathways

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2016-06-01

Our study showed that chromosome 1 gene mutations occur frequently in 1p-intact neuroblastoma, but these do not consistently abrogate the function of bonafide tumor suppressors residing on 1p.. Mutational Analysis of 1p Tumor Suppressors in 1p-intact Neuroblastoma

母细胞瘤遗传学

肿瘤抑制基因

Deletion of 1p is associated with poor prognosis in neuroblastoma, however selected 1p-intact patients still experience poor outcomes. Since mutations of 1p genes may produce deleterious functional ef

NIAID Data Ecosystem120

Additional file 2: Table S2. of Concordance of copy number loss and down-regulation of tumor suppressor genes: a pan-cancer study

肿瘤抑制基因

癌细胞研究

The enriched pathways and interactors for the 207 tumor suppress genes (TSGs) with frequent copy number loss (CNL). (XLSX 11 kb)

DataCite Commons2024-12-12 更新60

MYBL2 Is a Sub-haploinsufficient Tumor Suppressor Gene in Myeloid Malignancy

肿瘤抑制基因

髓系恶性肿瘤

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

NIAID Data Ecosystem50

Molecular Evolution of PTEN Pseudogenes in Mammals

哺乳动物伪基因进化

肿瘤抑制基因

Phosphatase and tensin homolog (PTEN) is a tumor-suppressor gene. PTEN pseudogene (PTENp) acts as an endogenous RNA, which regulates its parental gene by competitively binding to the 3’ UTR of PTEN ge

NIAID Data Ecosystem80

Transcription profiling of transfected A549 lung cancer cell line with new tumor supressor gen ARLTS1 in that shows a very low expression level in comparison with normal lung

肿瘤抑制基因

癌细胞转录组

We have transfected a new tumor suppresor gene named ARLTS1 in A549 lung cancer cell line that shows a very low expression level in comparison with normal lung. This line was transfected using the pMV

NIAID Data Ecosystem50

G0S2 functions as a tumor supressor through represssion of Myc signaling pathways

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