Fold changes of hepatic metabolites in mice fed HFD or/and PFOA exposure for 3 weeks.

Hepatic metabolites were analyzed by GC-TOF MS and HPLC-TOFMS (n = 7–8).aFold change (FC) was obtained by comparing those metabolites in perfluorooctanoic acid (PFOA) group, high fat diet (HFD) group and HFD-PFOA group to control group (CTRL) or HFD-PFOA group to PFOA group; FC with a value >1 indicates a relatively higher concentration present in PFOA group, HFD group or HFD-PFOA group while a value bp values from Student’s t-test.