Dental Plaque Targeted loci environmental

This study is the first to use high throughput amplicon sequencing of the ITS1 region to characterize the oral mycobiome associated with dental health and Early Childhood Caries. Furthermore, we utilized a site-specific sampling approach to measure changes in mycobiome composition through the progressive stages of the disease. A characterization of the fungal community as caries progress will allow for further investigation into the complex interactions between the bacterial and fungal microbiomes and how these interactions impact dental health and caries disease development and progression.