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A mechanism of cooling hot tumors: lactate attenuates inflammation in dendritic cells

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE164027
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The epigenetic status of H3K27Ac was comparable between Egr1 deficient and WT bone marrow-derived dendritic cells (BMDCs). We identified a region that suggested the interaction of EGR1 in the Cd80 promoter. We analysed the status of H3K27Ac and EGR1 in LPS and lactic acid (LA)-stimulated WT or Egr1 deficient BMDCs using ChIP-sequencing.
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2021-09-21
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