Dynamic Single Cell Transcriptomics Defines Kidney FGF23/KL Bioactivity and Novel Segment-Specific Inflammatory Targets

NIAID Data Ecosystem2026-05-02 收录

疾病靶点发现

生物活性分析

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE254601 数据链接链接失效反馈

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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

创建时间：

2025-03-28

Additional file 7 of QSAR-derived affinity fingerprints (part 1): fingerprint construction and modeling performance for similarity searching, bioactivity classification and scaffold hopping

化学信息学

生物活性分析

Additional file 7. Biological activity classification task. Average values of AUC and EF5 for individual sets in the CLASS data sets obtained using various settings (affinity cutoffs of 5-8, AD estima

DataCite Commons2020-08-25 更新90

Selective Regulation of Tuft Cell-Like Small Cell Lung Cancer by Novel Transcriptional Co-activators C11orf53 and COLCA2. Selective Regulation of Tuft Cell-Like Small Cell Lung Cancer by Novel Transcriptional Co-activators C11orf53 and COLCA2

小细胞肺癌亚型机制

疾病靶点发现

The DepMap project has generated a huge resource for investigating selectively essential genes, which represent potential cancer therapeutic targets. However, manually sorting out which of the hundred

NIAID Data Ecosystem20

DataSheet_12_FBXO9 Mediates the Cancer-Promoting Effects of ZNF143 by Degrading FBXW7 and Facilitates Drug Resistance in Hepatocellular Carcinoma.zip

癌症分子机制

疾病靶点发现

F-box proteins are critical for malignancy because they control the turnover of key proteins that govern multiple cellular processes. F-box protein 9 (FBXO9) belongs to the F-box protein family and ex

NIAID Data Ecosystem20

RNA-seq of nine canine prostate cancer cell lines reveals diverse therapeutic target signatures

疾病靶点发现

临床前模型

Background: Canine prostate adenocarcinoma (PAC) and transitional cell carcinoma (TCC) are typically characterized by metastasis and chemoresistance. Cell lines are important model systems for develop

NIAID Data Ecosystem20

Drug-likeness profile of the top 10 drugs.

疾病靶点发现

药物筛选

Pediatric acute-myeloid-leukemia (pAML) is an aggressive malignancy and the second most common blood cancer in children. In spite of significant advances in the frontline therapeutic approaches, appro

NIAID Data Ecosystem20

Dynamic Single Cell Transcriptomics Defines Kidney FGF23/KL Bioactivity and Novel Segment-Specific Inflammatory Targets

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