Expression data from patient female with acute promyelicytic leukemia

The objective of the present study is to describe the gene expression of acute promyelocytic leukemia and PML/RARA oncoprotein, in a pediatric female patient, according to their clinical characteristics, immunophenotype and karyotype We used microarrays to detail the clinic and evolution of leukemia with gene expression and identified biomarkers more importan found up or down regulated genes during this process. The study describes the unusual simultaneous presence of PML/RARA fusion gene bcr1, bcr2 and bcr3 transcripts, in a pediatric female patient diagnosed with APL, according to their clinical characteristics, immunophenotype, classical cytogenetic and prognosis. We included also, a functional implications analysis based on expression arrays.